Sequential Organ Failure Assessment (SOFA) Score

SOFA Score Calculator

Sequential Organ Failure Assessment  ·  ICU sepsis severity & mortality prediction

Respiration

PaO₂ (mmHg) Arterial oxygen partial pressure

FiO₂ (%) Fraction of inspired oxygen

Mechanical ventilation No Yes

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Coagulation · Liver · CNS

Platelets (×10³/µL) ≥ 150 100 – 149 50 – 99 20 – 49 < 20

Bilirubin (mg/dL) < 1.2 1.2 – 1.9 2.0 – 5.9 6.0 – 11.9 ≥ 12.0

Glasgow Coma Scale 15 13 – 14 10 – 12 6 – 9 < 6

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Cardiovascular

MAP / Vasoactive agents No hypotension (MAP ≥ 70 mmHg) MAP < 70 mmHg Dopamine ≤ 5 µg/kg/min or Dobutamine (any) Dopamine > 5, Epinephrine ≤ 0.1, or Norepinephrine ≤ 0.1 µg/kg/min Dopamine > 15, Epinephrine > 0.1, or Norepinephrine > 0.1 µg/kg/min

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Renal

Creatinine (mg/dL) or urine output < 1.2 mg/dL 1.2 – 1.9 mg/dL 2.0 – 3.4 mg/dL 3.5 – 4.9 mg/dL or UOP < 500 mL/day ≥ 5.0 mg/dL or UOP < 200 mL/day

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SOFA score

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Est. mortality

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Interpretation

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Mortality reference (Vincent et al.)

SOFA score	Est. ICU mortality	Risk
0 – 1	< 1%	Very low
2 – 3	2 – 5%	Low
4 – 5	6 – 10%	Moderate
6 – 7	15 – 20%	High
8 – 9	40 – 50%	Very high
10 – 11	50 – 60%	Critical
≥ 12	> 80%	Extreme

Based on Singer et al. (Sepsis-3, JAMA 2016) & Vincent et al. original SOFA criteria  ·  All calculations run locally  ·  No patient data stored or transmitted

Clinical references

• 1.Vincent JL, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med. 1996;22(7):707–710. doi:10.1007/BF01709751
• 2.Singer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801–810. doi:10.1001/jama.2016.0287
• 3.Shankar-Hari M, et al. Developing a New Definition and Assessing New Clinical Criteria for Septic Shock (Sepsis-3). JAMA. 2016;315(8):775–787.
• 4.Ferreira FL, et al. Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA. 2001;286(14):1754–1758.
• 5.Seymour CW, et al. Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):762–774.
• 6.Evans L, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Intensive Care Med. 2021;47(11):1181–1247. doi:10.1007/s00134-021-06506-y
• 7.Prescott HC, Angus DC. Enhancing Recovery From Sepsis: A Systematic Review. JAMA. 2018;319(1):62–75.

Frequently asked questions

Medical disclaimer

For educational and professional reference only. This SOFA Score Calculator is intended to assist qualified healthcare professionals in clinical decision-making. It is not a substitute for clinical judgment, direct patient assessment, or institutional protocols.

The predicted mortality ranges displayed are derived from published cohort studies and represent population-level estimates. Individual patient outcomes may differ significantly based on comorbidities, treatment interventions, local microbial ecology, and other factors not captured by this tool.

Serial SOFA scoring (trend over 48–72 hours) is more clinically informative than a single time-point score. A rising SOFA score of ≥ 2 points is a key diagnostic criterion for sepsis per Sepsis-3 consensus definitions (2016).

This tool does not store, transmit, or process any patient-identifiable information. All calculations occur entirely within the user's browser. The authors and publishers of this tool assume no liability for clinical decisions made based on its output. Always verify with current institutional guidelines and consult appropriate specialists.

Last reviewed against literature: January 2026. Surviving Sepsis Campaign 2021 guidelines incorporated.